As the cost of healthcare continues to rise, U.S. companies are grappling with how to address it most effectively. These businesses could learn a great deal from U.S. cities with the highest well-being.

The largest U.S. employers could reap about $22 billion in annual savings if their employees matched the smoking and obesity rates these top cities have achieved—savings from reductions in absenteeism due to poor health and smoking breaks and from lower healthcare costs.

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