The National Institute of Standards and Technology recently issued the first set of standard reference materials (SRM) in a planned series for the assessment of botanical dietary supplements. The dietary supplement industry has exploded in the past decade to about 29,000 products, with about 1,000 new products introduced each year, according to the Food and Drug Administration. In 2001, NIST began working with the FDA and the National Institute of Health’s Office of Dietary Supplements on a series of SRMs for popular botanical dietary supplements. Manufacturers of these supplements can use these materials for quality control and researchers can use them to ensure the accuracy of supplement laboratory analyses.

The new reference materials were designed primarily for quality control of supplements containing ephedra, a plant once widely used in weight-loss products. Ephedra products were pulled from the market in 2004, but the new test materials remain valuable to ensure that new products don’t contain the substance and because they can also be used to improve several key elements in other botanical supplements.

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