(Wittgas: Witten, Germany) -- Because leaky pharmaceutical packaging can endanger the shelf life and efficacy of packaged medicines, leak testing is a must. This can be easily and reliably done using Witt’s methylene blue test with the Leak-Master Easy.

As particularly sensitive products, medicines require high-quality packaging. Even the smallest leaks, invisible to the naked eye, can render the protective barrier of blister packs ineffective. Oxygen, moisture, and microorganisms can penetrate and make the medicines unusable.

To test the integrity and tightness of blister packs in particular, the packs are placed in a container with an ethanol-based test liquid containing methylene blue as a dye. The blue dye creeps into leaking packages and colors the contents a striking blue, making defective seals or blister cavities clearly identifiable. The method is suitable for detecting leaks with a size of about 10–20 µm.

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